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A condition called polycystic kidney disease runs in their family, and eventually the affected organs fail. That day has come.

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But if all finally goes as planned, Amy, at age 50, will become a living kidney donor to Laura, now 49, sometime before the end of the year at a Boston-area hospital. More than 90, people in the United States are on the kidney transplant waitlist.

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Adam Drake, a schoolteacher in Vancouver, British Columbia, fell into the unrelated match category with his recipient. Although Drake never had a second thought about donating, the process was long and not always smooth.

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Leading up to the procedure, he had to have many tests. Afterward, he developed a herniawhich meant opening him up again for a repair. Not all donors and recipients know one another.

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Only 19 and already on dialysisthe young patient was in an urgent situation. No one in her family was a match.

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Some members in the chat filled in online donor candidate forms to see if they might be. Waters, now age 33, ended up being the one. After a series of blood tests and a battery of health exams, much like the ones Drake described, Waters had her kidney removed for donation in March The surgery took about 3 hours. Her own hospital stay was only a night, and her recovery was event-free, allowing her to return to work within 2 weeks.

She and the recipient are now close friends.

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In some places, surgeons may still use a hand rather than instruments for removal, which requires a slightly larger opening. Regardless of the method, several steps are involved.

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Although the kidneys lie at the back of the body, surgeons now get to them through the abdomen, which requires filling the space with gas to see internal organs clearly. To reach the kidney from this entry point, surgeons must carefully move the sensitive large intestine out of the way to avoid damage. When it comes time to disconnect the kidney, there are three major connections to deal with: a large artery that runs from the aorta, a vein that drains blood from the kidney into the vena cava, and the ureter, which drains urine from the kidney to the bladder.

Before dealing with these big tubes, the surgeons will address the various smaller ones, sealing them up as they disconnect them.

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The whole process usually takes 2 to 3 hours, according to Sultan. One reason is that these kidneys may still have a little function to contribute, and the other is that removing organs is always risky. But he never wavered.

They now text each other a little celebratory note on the anniversary of the surgeries. This process continues in a chain of donations to matched recipients, with patients like Laura a hopeful recipient from an altruistic donor somewhere in the chain.

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In October, news broke that surgeons had successfully connected a genetically engineered pig kidney to a patient without detectable brain activity who was still on a ventilator. But despite this promising breakthrough, so-called pigney transplants are still likely years away. Without a living donor match, a patient needing a kidney will likely have to wait for years.

A dozen such patients die every day while waiting. Patients in kidney failure must have dialysis to stay alive, hooked up several times a week to a machine to filter their blood for them.

The fact that they went through this three times a week, sitting there for hours. A to Z Guides News.

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Stranger Who Matches Not all donors and recipients know one another. A Ticking Clock When it comes time to disconnect the kidney, there are three major connections to deal with: a large artery that runs from the aorta, a vein that drains blood from the kidney into the vena cava, and the ureter, which drains urine from the kidney to the bladder. They start preserving the organ as soon as possible by flushing a preservative into it.

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Drake, age 54, never considered not donating. The Long Wait Without a living donor match, a patient needing a kidney will likely have to wait for years. Could I have CAD? Missing Teeth? ZIP:

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